Ethanol → HCID 46849908, compound

HRID 2237444Notes

Reaction equation

HRID 2237444 reaction equation
C(OC([N:6]1[CH2:12][CH2:11][C:10]2[C:13]([CH3:20])=[C:14]([C:16]([CH3:19])([CH3:18])[CH3:17])[S:15][C:9]=2[CH2:8][CH2:7]1)=O)C.CCO.[OH-].[K+]>O>[C:16]([C:14]1[S:15][C:9]2[CH2:8][CH2:7][NH:6][CH2:12][CH2:11][C:10]=2[C:13]=1[CH3:20])([CH3:19])([CH3:18])[CH3:17]

Participants

5

Reactant 3

HCID 702EthanolHCID 14797Potassium HydroxideHCID 68473086HCID 68473086, compound

Product 1

HCID 46849908HCID 46849908, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
100 °C

Procedure

The product of step b) was treated with 2 mL each of EtOH and 40% aqueous KOH. After heating to 100° C. for 12 hours, the reaction was cooled, diluted with water, and extracted 2× into DCM. The title product was purified by preparative HPLC-MS. MS: ESI (positive): 224 (M+H).

Workup

  1. temperaturethe reaction was cooled
  2. extractionextracted 2× into DCM
  3. customThe title product was purified by preparative HPLC-MS

Sources & evidence

ORD record
ord-cf910cc00eaf41ad868313189653cbf7
Source dataset
uspto-grants-2010_05
Patent number
US07718647B2

Reaction notes

Loading…