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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 223772Generated: October 26, 2026

1,2-Epoxydodecane → 1-(2-Hydroxydodecyl)-2-(2-pyridyl)imidazole

https://huagongshe.com/reaction/223772

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-EpoxydodecaneHCID 17858—
Reactant2-(1H-imidazol-2-yl)pyridineHCID 589313—
CatalystWaterHCID 962—
Product1-(2-Hydroxydodecyl)-2-(2-pyridyl)imidazoleHCID 20520762—

Reaction Conditions

Temperature160 °C

Reaction Steps

A mixture of 14.5 g (0.1 mole) 2-(2-pyridyl)imidazole, 18.4 g (0.1 mole) 1,2-epoxydodecane and 3 drops of water was heated with stirring at about 160° C. under nitrogen for about one hour. The resulting product was then extracted with hot hexane and collected as yellow crystals which had a melting point of 62°-65° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04356309
Source datasetuspto-grants-1982_10
ORD IDord-a370c73d7c074116a7ccd29da8475232
Source noteuspto-grants-1982_10