HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Bromomethyl)quinolin-2(1H)-one → Carbostyril malonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Bromomethyl)quinolin-2(1H)-one | HCID 336706 | — |
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | Diethyl acetamide malonate | HCID 22466969 | — |
| Product | Carbostyril malonate | HCID 68583663 | — |
Reaction Steps
bromomethyl carbostyril (2) is reacted with diethylacetamide malonate (3) in the presence of a base such as sodium ethoxide to give carbostyril malonate compound (4);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07718805B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-34d9b3f7dcba4af4b2ee6d3d51ca181d |
| Source note | uspto-grants-2010_05 |