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HRID2238591

反应详情

EQUATION

反应方程式

HRID 2238591 的结构方程式

REACTANTS

反应物

2
反应SMILES：O[C@@H]1CCNC1
HCID2759337

(R)-3-Hydroxypyrrolidine

C4H9NO

反应SMILES：Cc1nc2c(OC3CCOc4ccccc43)cc(C(=O)O)cc2n1C
HCID68689166

未命名化合物

PRODUCTS

产物

1
反应SMILES：Cc1nc2c(OC3CCOc4ccccc43)cc(C(=O)N3CC[C@@H](O)C3)cc2n1C
HCID59303893

未命名化合物

收率 23%

PROCEDURE

实验过程

The title compound was prepared as a white solid in 23% yield (19 mg) from 4-(3,4-dihydro-2H-chromen-4-yloxy)-1,2-dimethyl-1H-benzimidazole-6-carboxylic acid (70 mg, 0.21 mmol, STEP 2 of Example 11) and (R)-(−)-3-pyrrolidinol (77 mg, 0.63 mmol) by the same manner in STEP 3 of Example 11: