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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2238591Generated: October 30, 2026

(R)-3-Pyrrolidinol → HCID 59303893, compound

https://huagongshe.com/reaction/2238591

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-3-PyrrolidinolHCID 2759337—
Reactant4-(3,4-Dihydro-2H-chromen-4-yloxy)-1,2-dimethyl-1H-benzimidazole-6-carboxylic acidHCID 68689166—
ProductHCID 59303893HCID 5930389323%

Reaction Steps

The title compound was prepared as a white solid in 23% yield (19 mg) from 4-(3,4-dihydro-2H-chromen-4-yloxy)-1,2-dimethyl-1H-benzimidazole-6-carboxylic acid (70 mg, 0.21 mmol, STEP 2 of Example 11) and (R)-(−)-3-pyrrolidinol (77 mg, 0.63 mmol) by the same manner in STEP 3 of Example 11:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07718809B2
Source datasetuspto-grants-2010_05
ORD IDord-c4c6279c98b04a428e8d4023889415df
Source noteuspto-grants-2010_05