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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2238789Generated: November 3, 2026

p-Anisoyl chloride → 2-Amino-4-(2-furyl)-5-(tetrahydropyran-4-ylcarbonyl)thiazole

https://huagongshe.com/reaction/2238789

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Anisoyl chlorideHCID 7477—
ReactantHCID 23144255HCID 23144255—
Product2-Amino-4-(2-furyl)-5-(tetrahydropyran-4-ylcarbonyl)thiazoleHCID 86612468—

Reaction Steps

In a manner similar to that in Example 456, by using 4-methoxybenzoyl chloride in place of cyclopropanecarbonyl chloride, the entitled Compound 463. (152 mg, 82%) was obtained as a grayish white solid from Compound 454 (125 mg, 0.450 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07718808B2
Source datasetuspto-grants-2010_05
ORD IDord-df3d6aeee7ee438db2fed9636fb12700
Source noteuspto-grants-2010_05