Methyl iodide → 6-Bromo-2,2,4,7-tetramethyl-4H-benzo[1,4]oxazin-3-one

HRID 2239246Notes

Reaction equation

HRID 2239246 reaction equation
[Br:1][C:2]1[C:3]([CH3:17])=[CH:4][C:5]2[O:10][C:9]([CH3:12])([CH3:11])[C:8](=[O:13])[N:7]([CH2:14]C)[C:6]=2[CH:16]=1.CI>>[Br:1][C:2]1[C:3]([CH3:17])=[CH:4][C:5]2[O:10][C:9]([CH3:11])([CH3:12])[C:8](=[O:13])[N:7]([CH3:14])[C:6]=2[CH:16]=1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 685847416-Bromo-4-ethyl-2,2,7-trimethyl-4H-benzo[1,4]oxazin-3-one

Product 1

HCID 685830856-Bromo-2,2,4,7-tetramethyl-4H-benzo[1,4]oxazin-3-one

Procedure

This was prepared using a procedure similar to that described to make Compound 1C, except using methyl iodide in Step 1C. MS (electrospray): mass calculated for C12H14BrNO2, 283.02; m/z found 284 [M+H]+.

Workup

  1. customThis was prepared

Sources & evidence

ORD record
ord-b3955ad1ca7247a99ec72a22352ce633
Source dataset
uspto-grants-2010_05
Patent number
US07723326B2

Reaction notes

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