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HRID2239309

反应详情

EQUATION

反应方程式

HRID 2239309 的结构方程式

REACTANTS

反应物

2
结构：CNCCN(C)C
HCID67338

1,2-Ethanediamine, N,N,N'-trimethyl-

C5H14N2

结构：Cc1nc2c(OC3CCOc4cc(F)cc(F)c43)cc(C(=O)O)cc2[nH]1
HCID68574559

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc2c(OC3CCOc4cc(F)cc(F)c43)cc(C(=O)N(C)CCN(C)C)cc2[nH]1
HCID58900197

未命名化合物

收率 13%

PROCEDURE

实验过程

The title compound was prepared as a white solid (10 mg, 13% yield for 3 steps) from 4-[(5,7-difluoro-3,4-dihydro-2H-chromen-4-yl)oxy]-2-methyl-1H-benzimidazole-6-carboxylic acid (100 mg, crude, STEP 4 in Example 4) and N,N,N′-trimethyl-1,2-ethanediamine (45 mg, 0.44 mmol) by the same manner in STEP 5 of Example 1.