Dimethylamine → HCID 68408168, compound

HRID 2239474Notes

Reaction equation

HRID 2239474 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8](Cl)(=[O:10])=[O:9])=[C:4]([O:12][C:13]([F:16])([F:15])[F:14])[CH:3]=1.[CH3:17][NH:18][CH3:19]>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:18]([CH3:19])[CH3:17])(=[O:10])=[O:9])=[C:4]([O:12][C:13]([F:16])([F:15])[F:14])[CH:3]=1

Participants

3

Reactant 2

HCID 674DimethylamineHCID 27364214-Bromo-2-(Trifluoromethoxy)Benzene-1-Sulfonyl Chloride

Product 1

HCID 68408168HCID 68408168, compoundYield 81%

Procedure

According to general procedure A, 4-Bromo-2-trifluoromethoxy-benzenesulfonyl chloride (0.35 g, 1.03 mmol) and dimethylamine (10 mL, 33% in ethanol) were stirred in sealed tube for 16 hours. 4-Bromo-N,N-dimethyl-2-trifluoromethoxy-benzenesulfonamide (0.29 g, 81%) was provided after purification. Mp. 55-58° C. MS (ESI) m/z 348.14.

Sources & evidence

ORD record
ord-f8929837585e426f9e5eb1a6877ef9f3
Source dataset
uspto-grants-2010_05
Patent number
US07723332B2

Reaction notes

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