HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxyphenol → HCID 67241876, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxyphenol | HCID 9015 | — |
| Reactant | [(2-tert-Butyl-1,1-dioxido-3-oxo-5-phenyl-2,3-dihydroisothiazol-4-yl)amino]acetic acid | HCID 67241765 | — |
| Product | HCID 67241876 | HCID 67241876 | 21% |
Reaction Steps
The title compound was prepared from [(2-tert-butyl-1,1-dioxido-3-oxo-5-phenyl-2,3-dihydroisothiazol-4-yl)amino]acetic acid and 4-methoxyphenol as described for Example 171 affording the title compound (28 mg, 21%). 1H NMR (CDCl3, 400 MHz) δ 1.71 (s, 9H), 3.77 (s, 3H), 3.81 (d, 2H), 5.78 (t, 1H), 6.85 (dd, 4H), 7.44-7.51 (m, 5H). 13C NMR (CDCl3, 100 MHz) δ 27.8, 45.6, 55.8, 61.9, 110.1, 114.7, 122.0, 124.5, 129.1, 130.2, 131.6, 134.8, 143.6, 157.8, 159.2, 167.8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07723333B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-3af7fbcaa72c4323a348973386d410cc |
| Source note | uspto-grants-2010_05 |