HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59304987, compound → 2-Fluoro-N1-(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)benzene-1,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59304987 | HCID 59304987 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Fluoro-N1-(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)benzene-1,4-diamine | HCID 59305011 | — |
Reaction Steps
23 mg (80 μmol) of N-(2-fluoro-4-nitrophenyl)-3-methyl-1H-pyrrolo[2,3-b]pyridine-4-amine are dissolved in 12 ml of ethanol. 19 mg (19 μmol) of 10% palladium-on-carbon are added and the mixture is hydrogenated in a hydrogen atmosphere at atmospheric pressure overnight. The mixture is filtered through Celite and the solvent is removed under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07723347B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-a1e9fd35ac4643d29ccd6b2ee4b15868 |
| Source note | uspto-grants-2010_05 |