HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59304976, compound → 2-Fluoro-N1-(1-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)benzene-1,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59304976 | HCID 59304976 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Tetrahydrofuran ethanol | HCID 21873804 | — |
| Product | 2-Fluoro-N1-(1-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)benzene-1,4-diamine | HCID 59305022 | — |
Reaction Steps
195 mg (0.68 mmol) of N-(2-fluoro-4-nitrophenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridine-4-amine are dissolved in 10 ml of a mixture of ethanol/THF. (1:1). 15 mg (0.07 mmol) of platinum(IV) oxide are added, and the mixture is stirred under a hydrogen atmosphere at atmospheric pressure overnight. The suspension is then filtered through Celite, the Celite is washed with a little ethanol and the solvent is removed under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07723347B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-ec2b02c0d36b49069b4e70a1ecfae85c |
| Source note | uspto-grants-2010_05 |