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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2240236Generated: October 30, 2026

HCID 59304976, compound → 2-Fluoro-N1-(1-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)benzene-1,4-diamine

https://huagongshe.com/reaction/2240236

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59304976HCID 59304976—
CatalystAdams' catalystHCID 345198—
SolventTetrahydrofuran ethanolHCID 21873804—
Product2-Fluoro-N1-(1-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)benzene-1,4-diamineHCID 59305022—

Reaction Steps

195 mg (0.68 mmol) of N-(2-fluoro-4-nitrophenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridine-4-amine are dissolved in 10 ml of a mixture of ethanol/THF. (1:1). 15 mg (0.07 mmol) of platinum(IV) oxide are added, and the mixture is stirred under a hydrogen atmosphere at atmospheric pressure overnight. The suspension is then filtered through Celite, the Celite is washed with a little ethanol and the solvent is removed under reduced pressure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07723347B2
Source datasetuspto-grants-2010_05
ORD IDord-ec2b02c0d36b49069b4e70a1ecfae85c
Source noteuspto-grants-2010_05