HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → spiro[indene-1,4'-piperidin]-3(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Tert-butyl 3-oxo-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylate | HCID 18673579 | — |
| Product | spiro[indene-1,4'-piperidin]-3(2H)-one | HCID 18467061 | — |
Reaction Steps
N-boc-1-[4-spiro-piperidine]-3-indanone and trifluoroacetic acid were processed according to the method of Example 137D to provide the product. No purification was required. MS (ESI+) m/z 202 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07723367B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-5727a019f1ed40ef8146731beed4a457 |
| Source note | uspto-grants-2010_05 |