HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-4-chlorobutane → 1-(4-Chlorobutyl)-7,8-dimethoxy-3,4-dihydro-1H-1-benzazepine-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-4-chlorobutane | HCID 81364 | — |
| Reactant | 7,8-dimethoxy-3,4-dihydro-1H-1-benzazepine-2,5-dione | HCID 23000064 | — |
| Product | 1-(4-Chlorobutyl)-7,8-dimethoxy-3,4-dihydro-1H-1-benzazepine-2,5-dione | HCID 68583156 | 36.1% |
Reaction Steps
Analogously to Example 1, reaction of 7,8-dimethoxy-3,4-dihydro-1H-1-benzazepine-2,5-dione (1.70 mmol, 0.40 g, preparation according to Arch. Pharm. 1991, 324, 579) and bromo-4-chlorobutane (2.04 mmol, 0.35 g) afforded 0.20 g of the contaminated title compound. The compound is reacted further without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07723384B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-4a217386314b4a54950ba8c21500f7a6 |
| Source note | uspto-grants-2010_05 |