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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2240620Generated: November 1, 2026

2-tert-Butyl-4-cyclobutyl-6-(piperazin-1-yl)pyrimidine → HCID 68583918, compound

https://huagongshe.com/reaction/2240620

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-tert-Butyl-4-cyclobutyl-6-(piperazin-1-yl)pyrimidineHCID 66673390—
Reactant1-(4-chlorobutyl)-3,4-dihydro-1H-benzo[b]azepine-2,5-dioneHCID 68582896—
ProductHCID 68583918HCID 68583918—

Reaction Steps

Analogously to Example 3b, reaction of 2-tert-butyl-4-cyclobutyl-6-piperazin-1-ylpyrimidine (1.97 mmol, 0.54 g) with 1-(4-chlorobutyl)-3,4-dihydro-1H-1-benzazepine-2,5-dione afforded 0.39 g of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07723384B2
Source datasetuspto-grants-2010_05
ORD IDord-4af34a43263e41678ddd93a66c5da859
Source noteuspto-grants-2010_05