HRID2240622

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11460084

2,4-di-tert-butyl-6-piperazin-1-ylpyrimidine

C16H28N4

HCID68582896

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)c1cc(N2CCN(CCCCN3C(=O)CCC(=O)c4ccccc43)CC2)nc(C(C)(C)C)n1.Cl

HCID68583151

未命名化合物

PROCEDURE

实验过程

Analogously to Example 3b, reaction of 2,4-di-tert-butyl-6-piperazin-1-ylpyrimidine (1.26 mmol, 0.35 g) with 1-(4-chlorobutyl)-3,4-dihydro-1H-1-benzazepine-2,5-dione afforded 0.04 g of the title compound.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-cffaf88a4d5b42d2a5f19383cc90998b
来源数据集: uspto-grants-2010_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07723384B2
来源说明: uspto-grants-2010_05

反应 SMILES

[C:1]([C:5]1[N:10]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[CH:8]=[C:7]([N:15]2[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]2)[N:6]=1)([CH3:4])([CH3:3])[CH3:2].[Cl:21][CH2:22][CH2:23][CH2:24][CH2:25][N:26]1[C:32]2[CH:33]=[CH:34][CH:35]=[CH:36][C:31]=2[C:30](=[O:37])[CH2:29][CH2:28][C:27]1=[O:38]>>[ClH:21].[C:1]([C:5]1[N:6]=[C:7]([N:15]2[CH2:16][CH2:17][N:18]([CH2:22][CH2:23][CH2:24][CH2:25][N:26]3[C:32]4[CH:33]=[CH:34][CH:35]=[CH:36][C:31]=4[C:30](=[O:37])[CH2:29][CH2:28][C:27]3=[O:38])[CH2:19][CH2:20]2)[CH:8]=[C:9]([C:11]([CH3:13])([CH3:14])[CH3:12])[N:10]=1)([CH3:2])([CH3:3])[CH3:4]