HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Di-tert-butyl-6-piperazin-1-ylpyrimidine → 1-{4-[4-(2,6-Di-tert-butylpyrimidin-4-yl)piperazin-1-yl]butyl}-3,4-dihydro-1H-1-benzazepine-2,5-dione hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Di-tert-butyl-6-piperazin-1-ylpyrimidine | HCID 11460084 | — |
| Reactant | 1-(4-chlorobutyl)-3,4-dihydro-1H-benzo[b]azepine-2,5-dione | HCID 68582896 | — |
| Product | 1-{4-[4-(2,6-Di-tert-butylpyrimidin-4-yl)piperazin-1-yl]butyl}-3,4-dihydro-1H-1-benzazepine-2,5-dione hydrochloride | HCID 68583151 | — |
Reaction Steps
Analogously to Example 3b, reaction of 2,4-di-tert-butyl-6-piperazin-1-ylpyrimidine (1.26 mmol, 0.35 g) with 1-(4-chlorobutyl)-3,4-dihydro-1H-1-benzazepine-2,5-dione afforded 0.04 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07723384B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-cffaf88a4d5b42d2a5f19383cc90998b |
| Source note | uspto-grants-2010_05 |