HuagongsheHuagongshe Chemistry Print Report · For research reference only
Octahydropyrrolo(1,2-a)pyrazine → 1-[4-(Hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)butyl]-3,4-dihydro-1H-1-benzazepine-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Octahydropyrrolo(1,2-a)pyrazine | HCID 558578 | — |
| Reactant | 1-(4-chlorobutyl)-3,4-dihydro-1H-benzo[b]azepine-2,5-dione | HCID 68582896 | — |
| Product | 1-[4-(Hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)butyl]-3,4-dihydro-1H-1-benzazepine-2,5-dione | HCID 68583801 | 35.2% |
Reaction Steps
Analogously to the method for Example 12b, reaction of 1-(4-chlorobutyl)-3,4-dihydro-1H-1-benzazepine-2,5-dione (0.40 mmol, 0.11 g) and octahydropyrrolo[1,2-a]pyrazine (0.40 mmol, 0.05 g) afforded 0.05 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07723384B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-f061a8e9d5af4fb5a2b73350a3ff0dbf |
| Source note | uspto-grants-2010_05 |