HRID2240632

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C1CCC(=O)N(CCCCN2C[C@@H]3CN(C(=O)OCc4ccccc4)C[C@@H]32)c2ccccc21

HCID86615127

未命名化合物

HCID178418361

未命名化合物

PRODUCTS

生成物

结构：O=C1CCC(=O)N(CCCCN2C[C@H]3CNC[C@@H]32)c2ccccc21

HCID68583400

未命名化合物

收率 67.9%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

In the presence of Pd/C (0.01 g, 10%), benzyl (1R,5R)-6-[4-(2,5-dioxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)butyl]-3,6-diazabicyclo[3.2.0]heptane-3-carboxylate from Example 65 (0.45 mmol, 0.21 g) in methanol (7 ml) was reacted with hydrogen to obtain 0.10 g of the title compound.