HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86615127, compound → HCID 68583400, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86615127 | HCID 86615127 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 68583400 | HCID 68583400 | 67.9% |
Reaction Steps
In the presence of Pd/C (0.01 g, 10%), benzyl (1R,5R)-6-[4-(2,5-dioxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)butyl]-3,6-diazabicyclo[3.2.0]heptane-3-carboxylate from Example 65 (0.45 mmol, 0.21 g) in methanol (7 ml) was reacted with hydrogen to obtain 0.10 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07723384B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-7c9b68b363dd4ce7b9cb0056feb591ba |
| Source note | uspto-grants-2010_05 |