Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2240633Generated: October 31, 2026

1-(2,3-Dichlorophenyl)piperazine → 1-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl}-3,4-dihydro-1H-benzo[b]azepine-2,5-dione

https://huagongshe.com/reaction/2240633

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2,3-Dichlorophenyl)piperazineHCID 851833—
Reactant1-(4-chlorobutyl)-3,4-dihydro-1H-benzo[b]azepine-2,5-dioneHCID 68582896—
Product1-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl}-3,4-dihydro-1H-benzo[b]azepine-2,5-dioneHCID 68583920—

Reaction Steps

Analogously to Example 3b, reaction of 1-(4-chlorobutyl)-3,4-dihydro-1H-benzo[b]azepine-2,5-dione with 1-(2,3-dichlorophenyl)piperazine afforded the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07723384B2
Source datasetuspto-grants-2010_05
ORD IDord-3185389a5e0441c6a1bb7a3281d2f5ea
Source noteuspto-grants-2010_05