Trimethylsilylacetylene → 2-Fluoro-5-((trimethylsilyl)ethynyl)benzonitrile

Participants

Reaction Steps

The title compound was prepared in substantially the same manner as described in Example 1, step 3 starting from 2-Fluoro-5-iodo-benzonitrile (1.0 g, 4.14 mmol), and Ethynyl-trimethyl-silane (0.487 g, 4.97 mmol), and was obtained as a waxy brown solid, (0.90 g, 99%), identified by NMR and mass spectral analyses. MS (EI+): 216 (M+).

Provenance & Evidence