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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2241010Generated: November 2, 2026

Ethanol → HCID 25125324, compound

https://huagongshe.com/reaction/2241010

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantSodium CarbonateHCID 10340—
ReactantHCID 67538272HCID 67538272—
ReactantHCID 178485118HCID 178485118—
ProductHCID 25125324HCID 25125324—

Reaction Steps

This compound was made in a similar manner to Example 89 Step 8 using 1-(4-(difluoromethoxy)phenyl)-2-m-tolylethane-1,2-dione (1.45 g, 5.0 mmol) from the previous step, 1-methylguanidine hydrochloride (821 mg, 7.5 mmol), Na2CO3 (795 mg, 7.5 mmol), and EtOH (10 mL) to provide 1.04 g, 60%, of the title compound as a beige foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07723368B2
Source datasetuspto-grants-2010_05
ORD IDord-7378f13cb24f47d6acdefdbec2328f6b
Source noteuspto-grants-2010_05