2-Bromoethyl methyl ether → HCID 60043433, compound

HRID 2241412Notes

Reaction equation

HRID 2241412 reaction equation
[N:1]1([C:7]([O:9][C:10]([CH3:13])([CH3:12])[CH3:11])=[O:8])[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.Br[CH2:15][CH2:16][O:17][CH3:18]>>[CH3:18][O:17][CH2:16][CH2:15][N:4]1[CH2:5][CH2:6][N:1]([C:7]([O:9][C:10]([CH3:13])([CH3:12])[CH3:11])=[O:8])[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 809722-Bromoethyl methyl etherHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 60043433HCID 60043433, compoundYield 908.6%

Procedure

Prepared from tert-butyl piperazine-1-carboxylate (1.02 g, 5.50 mmol) and 1-bromo-2-methoxyethane (0.695 g, 5.0 mmol) according to the procedure described for Example 138, Step A. The product was obtained as a waxy solid (11.10 g, 89%).

Sources & evidence

ORD record
ord-9c13768d1d2841ccb5f289aab03f71e8
Source dataset
uspto-grants-2010_05
Patent number
US07723330B2

Reaction notes

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