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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2241533Generated: November 2, 2026

1-Cyclobutylpiperazine → HCID 24756897, compound

https://huagongshe.com/reaction/2241533

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-CyclobutylpiperazineHCID 4738602—
Reactant2-(Morpholine-4-carbonyl)-1-(2,2,2-trifluoro-ethyl)-1H-indole-5-carboxylic acidHCID 68681581—
ProductHCID 24756897HCID 2475689750%

Reaction Steps

The title compound was synthesized in analogy to example 46, intermediate e), from 2-(morpholine-4-carbonyl)-1-(2,2,2-trifluoro-ethyl)-1H-indole-5-carboxylic acid and 1-cyclobutylpiperazine (commercially available), to give the desired product as a white solid (50%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07723325B2
Source datasetuspto-grants-2010_05
ORD IDord-6ff48cc60a924489b1695a91c73fc283
Source noteuspto-grants-2010_05