Allyl iodide → HCID 59203879, compound

HRID 2241832Notes

Reaction equation

HRID 2241832 reaction equation
[Cl:1][C:2]1[CH:9]=[C:8]([O:10][C@@H:11]2[CH2:15][CH2:14][CH2:13][C@@H:12]2[OH:16])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH2:17](I)[CH:18]=[CH2:19]>>[CH2:19]([O:16][C@H:12]1[CH2:13][CH2:14][CH2:15][C@H:11]1[O:10][C:8]1[CH:7]=[CH:6][C:3]([C:4]#[N:5])=[C:2]([Cl:1])[CH:9]=1)[CH:18]=[CH2:17]

Participants

3

Reactant 2

HCID 11166Allyl iodideHCID 68546191HCID 68546191, compound

Product 1

HCID 59203879HCID 59203879, compoundYield 11.8%

Procedure

The product of Example 34, Step A (87 mg) was alkylated with allyl iodide (73.6 mg) according to the procedure of Example 34, Step B to give 12 mg of the title compound.

Sources & evidence

ORD record
ord-5a4a2442e5e04d558eb6665209eb4649
Source dataset
uspto-grants-2010_03
Patent number
US07670613B2

Reaction notes

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