HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → HCID 86610297, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | HCID 12004141 | HCID 12004141 | — |
| Product | HCID 86610297 | HCID 86610297 | — |
Reaction Steps
The weight of the resulting product was 311 g, or about 91.6% yield. NMR analysis indicated that the compound was the disuccinate salt form of 5-fluoro-4-methoxy-8-(4-(4-(6-methoxy-quinolin-8-yl)-piperazin-1-yl)-piperidin-1-yl)-2-trifluoromethyl-quinoline. In addition, residual solvents were found at concentrations of 0.047% for acetone, 0.027% for THF, and 0.14% for water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07671056B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-7c0a634077784ae3b8edb4141402a65c |
| Source note | uspto-grants-2010_03 |