HuagongsheHuagongshe Chemistry Print Report · For research reference only
Fexofenadine → Fexofenadine Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Fexofenadine | HCID 3348 | — |
| Reactant | Hydrochloride methanol | HCID 21893726 | — |
| Product | Fexofenadine Hydrochloride | HCID 63002 | — |
Reaction Steps
The diluted HCl/methanol solution was cooled (T<10° C.). Fexofendine base (50 grams) (1.88% H2O) was reacted with the diluted HCl/methanol solution, to form a fexofenadine-HCl solution. The molar ratio between fexofenadine-base and HCl was 1:1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07671071B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-21c641558b9f423b91c0580f697bb11e |
| Source note | uspto-grants-2010_03 |