Methanesulfonic Acid → N-[amino-(N'-pyridin-2-yl-hydrazino)-methylene]-4-methylbenzenesulfonamide

HRID 2242154Notes

Reaction equation

C[C:2]1[CH:6]=[C:5]([CH3:7])[N:4]([C:8](=[NH:20])[NH:9][S:10]([C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][CH:14]=2)(=[O:12])=[O:11])[N:3]=1.CS(O)(=O)=O.[NH:26]([C:28]1C=CC=CN=1)N>>[NH2:20][C:8]([NH:4][NH:3][C:2]1[CH:6]=[CH:5][CH:7]=[CH:28][N:26]=1)=[N:9][S:10]([C:13]1[CH:14]=[CH:15][C:16]([CH3:19])=[CH:17][CH:18]=1)(=[O:11])=[O:12]

Participants

Reactant 3

HCID 6395Methanesulfonic Acid

HCID 786452-Hydrazinopyridine

HCID 178427489N-[(3,5-dimethylpyrazol-1-yl)-iminomethyl]-4-methylbenzene-sulfonamide

Product 1

HCID 67176173N-[amino-(N'-pyridin-2-yl-hydrazino)-methylene]-4-methylbenzenesulfonamide

Procedure

The compound of Example 9 was prepared according to the accompanying synthesis procedure from 0.5 ml of N-[(3,5-dimethylpyrazol-1-yl)-iminomethyl]-4-methylbenzene-sulfonamide solution (0.2 M, acetonitrile) with 19 mg of methanesulfonic acid and 0.5 ml of 2-hydrazinopyridine solution (1.0 M, acetonitrile) and filed in a substance databank. Calculated mol. wt. 305.36; found mol. wt. (M+H) 306.1; 621.6 (Dimer)

Sources & evidence

ORD record: ord-5c662cc0c88a43fbb72dae94a5ee4310
Source dataset: uspto-grants-2010_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07671074B2

Reaction notes

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