Methanesulfonic Acid → HCID 178513457, compound

HRID 2242164Notes

Reaction equation

HRID 2242164 reaction equation
[CH3:1][C:2]1[CH:6]=[C:5](C)[N:4]([C:8](=[NH:20])[NH:9][S:10]([C:13]2[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=2)(=[O:12])=[O:11])N=1.CS(O)(=O)=O.[N:26]1C=CC=[CH:28][C:27]=1CN>>[NH2:20][C:8]([NH:4][CH2:5][C:6]1[CH:2]=[CH:1][CH:28]=[CH:27][N:26]=1)=[N:9][S:10]([C:13]1[CH:14]=[CH:15][C:16]([Cl:19])=[CH:17][CH:18]=1)(=[O:11])=[O:12]

Participants

4

Reactant 3

HCID 6395Methanesulfonic AcidHCID 195092-PyridinemethanamineHCID 178426541HCID 178426541, compound

Product 1

HCID 178513457HCID 178513457, compound

Procedure

The compound of Example 21 was prepared according to the accompanying synthesis procedure from 0.5 ml of N-[(3,5-dimethylpyrazol-1-yl)-iminomethyl]-4-chlorobenzene-sulfonamide solution (0.2 M, acetonitrile) with 19 mg of methanesulfonic acid and 0.5 ml of 2-picolylamine solution (1.0 M, acetonitrile) and filed in a substance databank. Calculated mol. wt. 327.79; found mol. wt. (M+H) 328.3; 655.6 (Dimer)

Sources & evidence

ORD record
ord-3c61a2f55bb04fb5bb81046881834bb0
Source dataset
uspto-grants-2010_03
Patent number
US07671074B2

Reaction notes

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