Methanesulfonic Acid → HCID 178427491, compound

HRID 2242166Notes

Reaction equation

C[C:2]1[CH:6]=[C:5](C)[N:4]([C:8](=[NH:20])[NH:9][S:10]([C:13]2[CH:18]=[CH:17][C:16](Cl)=[CH:15][CH:14]=2)(=[O:12])=[O:11])[N:3]=1.[CH3:21]S(O)(=O)=O.N1C=C[CH:29]=[C:28](CN)[CH:27]=1>>[NH2:20][C:8]([NH:4][CH2:5][C:6]1[CH:2]=[N:3][CH:27]=[CH:28][CH:29]=1)=[N:9][S:10]([C:13]1[CH:14]=[CH:15][C:16]([CH3:21])=[CH:17][CH:18]=1)(=[O:11])=[O:12]

Participants

Reactant 3

HCID 6395Methanesulfonic Acid

HCID 310183-Pyridinemethanamine

HCID 178426541HCID 178426541, compound

Product 1

HCID 178427491HCID 178427491, compound

Procedure

The compound of Example 23 was prepared according to the accompanying synthesis procedure from 0.5 ml of N-[(3,5-dimethylpyrazol-1-yl)-iminomethyl]-4-chlorobenzene-sulfonamide solution (0.2 M, acetonitrile) with 19 mg of methanesulfonic acid and 0.5 ml of 3-picolylamine solution (1.0 M, acetonitrile) and filed in a substance databank. Calculated mol. wt. 304.37; found mol. wt. (M+H) 305.3; 609.2 (Dimer)

Sources & evidence

ORD record: ord-985aa49d350e4d1a8d0e7531ecc4c106
Source dataset: uspto-grants-2010_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07671074B2

Reaction notes

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