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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2242367Generated: November 2, 2026

(1R,2R)-2-aminocyclopentan-1-ol hydrochloride → HCID 59205402, compound

https://huagongshe.com/reaction/2242367

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1R,2R)-2-aminocyclopentan-1-ol hydrochlorideHCID 12886906—
Reactant5-cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acidHCID 68543106—
ProductHCID 59205402HCID 59205402—

Reaction Steps

The title compound was prepared using 5-cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid [prepared from 3-(trifluoromethoxy)benzyl bromide and ethyl 5-cyanoindole-2-carboxylate] and trans-2-aminocyclopentanol hydrochloride in a manner similar to that described in Example 11.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07671080B2
Source datasetuspto-grants-2010_03
ORD IDord-1c874f66717b4889a0f0b0cb37ee8956
Source noteuspto-grants-2010_03