HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Amino-2-butanol → 5-Cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid (2-hydroxy-butyl)amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Amino-2-butanol | HCID 26107 | — |
| Reactant | 5-cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid | HCID 68543106 | — |
| Product | 5-Cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid (2-hydroxy-butyl)amide | HCID 59205433 | — |
Reaction Steps
The title compound was prepared using 5-cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid [prepared from 3-(trifluoromethoxy)benzyl bromide and ethyl 5-cyanoindole-2-carboxylate] and 1-amino-2-butanol in a manner similar to that described in Example 11.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07671080B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-84b0622df3604869806fddfe8bac41d8 |
| Source note | uspto-grants-2010_03 |