HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylcarbodiimide → HCID 178509448, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylcarbodiimide | HCID 12734 | — |
| Reactant | 5-cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid | HCID 68543106 | — |
| Reactant | HCID 178479278 | HCID 178479278 | — |
| Product | HCID 178509448 | HCID 178509448 | — |
Reaction Steps
The title compound was prepared using 5-cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid [prepared from 3-(trifluoromethoxy)benzyl bromide and ethyl 5-cyanoindole-2-carboxylate] and trans-4-aminocyclohexanol hydrochloride in a manner similar to that described in Example 11 but using 1,3-diisopropylcarbodiimide instead of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07671080B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-048d7b09a04b466f88196b88ac8f4a25 |
| Source note | uspto-grants-2010_03 |