Phosphorus oxychloride → HCID 2776908, compound

HRID 2242857Notes

Reaction equation

HRID 2242857 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[C:17](O)=[C:16]3[C:11]([CH:12]=[CH:13][CH:14]=[CH:15]3)=[N:10]2)=[CH:5][CH:4]=1.O=P(Cl)(Cl)[Cl:21]>O>[Cl:21][C:17]1[N:9]([C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)[N:10]=[C:11]2[C:16]=1[CH:15]=[CH:14][CH:13]=[CH:12]2

Participants

4

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 178492068HCID 178492068, compound

Product 1

HCID 2776908HCID 2776908, compoundYield 67%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
80 °C

Procedure

To a mixture of the product from step 2 (12.0 g, 0.05 mol) in acetanotrile (250 mL) was added POCl3 (11.5 g, 0.74 mol), and heated to 80° C. for 4 h. After the reaction mixture was cooled to room temperature, water (500 ml) was added. The product was collected on a filter, and washed with water. After dried under vacuum, the title compound (8 g, 67%) was obtained; MS (ESI+) m/z 259 (M+1, 100).

Workup

  1. temperatureAfter the reaction mixture was cooled to room temperature
  2. customThe product was collected on a filter
  3. washwashed with water
  4. customAfter dried under vacuum

Sources & evidence

ORD record
ord-c0d66ba744c847c9b2db9581a4177df1
Source dataset
uspto-grants-2010_03
Patent number
US07674802B2

Reaction notes

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