Sodium Hydroxide → HCID 68707042, compound

Participants

Reaction Steps

The title compound was prepared from product from step 1 (0.2 g, 0.5 mmol) and NaOH (50% in water, 0.080 g, 1.0 mmol) using the procedure of Step 6 of the Example 4 to provide the title compound (0.2 g, 60%). 1H NMR (400 MHz, DMSO) 7.68-7.59 (m, d, J=8.8 Hz, 4H), 7.42-7.38 (m, 1H), 7.24-7.17 (m, d, J=8.8 Hz, 3H), 4.17 (t, J=6 Hz, 2H), 3.27 (m, 4H), 2.77 (m, s, 5H), 2.18 (m, 2H); LC/MS (ESI+) m/z: 99%.

Provenance & Evidence