HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 1-(m-Chlorophenyl)-3-methyl-3-azabicyclo[3.1.0]hexane hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 1-(3-Chlorophenyl)-3-azabicyclo[3.1.0]hexane Hydrochloride | HCID 12719845 | — |
| Product | 1-(m-Chlorophenyl)-3-methyl-3-azabicyclo[3.1.0]hexane hydrochloride | HCID 12891362 | — |
Reaction Steps
By the method of Example 10, 1-(m-chlorophenyl)-N-methyl-1,2-cyclopropanedicarboximide, m.p. 72°-73° C., prepared from 1-(m-chlorophenyl)-1,2-cyclopropanedicarboximide (Example 6) and methyl iodide gives 1-(m-chlorophenyl)-3-methyl-3-azabicyclo[3.1.0]hexane hydrochloride as colorless crystals, m.p. 180°-182° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04231935 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-d5f7ffabf2054bcd806513ddadf8c3f0 |
| Source note | uspto-grants-1980_11 |