反应详情

A mixture of 8-phenyloctyl chloride (4.4 g), sodium iodide (5.34 g) and acetone (20 ml) was heated under reflux for 20 hours. Evaporated, water (20 ml) added and extracted with diethyl ether (20 ml). The extracts were dried, filtered and evaporated to a pale yellow liquid (5.5 g). Distilled to give 8-phenyloctyl iodide, b.p. 200° C. (air bath temperature) at 0.1 mBar.

1. temperaturewas heated
2. temperatureunder reflux for 20 hours
3. customEvaporated
4. additionwater (20 ml) added
5. extractionextracted with diethyl ether (20 ml)
6. customThe extracts were dried
7. filtrationfiltered
8. customevaporated to a pale yellow liquid (5.5 g)
9. distillationDistilled