HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl isocyanate → HCID 43520595, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl isocyanate | HCID 8022 | — |
| Reactant | 2-Amino-6-bromopyridine | HCID 300809 | — |
| Reactant | 6-(3-Ethylureido)pyridine-3-boronic acid pinacol ester | HCID 59208434 | — |
| Product | HCID 43520595 | HCID 43520595 | — |
Reaction Steps
The title compound was synthesized by a method analogous to Intermediate 1 synthesis starting with 6-bromopyridin-2-amine and ethyl isocyanate. The crude residue was purified by flash chromatography (EtOAc/hexanes as eluent). MS (ESP): 245 (M+H+) for C8H10BrN3O; NMR: 1.08 (t, 3H), 3.16 (m, 2H), 7.26 (d, 1H), 7.64 (s, 1H), 7.75 (s, 1H), 8.08 (d, 1H), 9.29 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07674801B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-cf1e30c5badf4ea3ba3ef05481626e8d |
| Source note | uspto-grants-2010_03 |