Lawesson's reagent → HCID 59208486, compound

HRID 2243065Notes

Reaction equation

HRID 2243065 reaction equation
[Br:1][C:2]1[C:3]([C:14](=[S:16])[NH2:15])=[CH:4][C:5]([NH:8][C:9]([NH:11][CH2:12][CH3:13])=[O:10])=[N:6][CH:7]=1.[CH3:17]OC1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=S)=CC=1>C1COCC1>[Br:1][C:2]1[C:3]([C:14](=[S:16])[NH2:15])=[CH:4][C:5]([NH:8][C:9]([NH:11][CH:12]([CH3:17])[CH3:13])=[O:10])=[N:6][CH:7]=1

Participants

4

Reactant 2

HCID 87949Lawesson's reagentHCID 59208439AZD7118 Bromo Thioamide

Product 1

HCID 59208486HCID 59208486, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The title compound was synthesized by a method analogous to the synthesis of Intermediate 42 starting with Intermediate 46 and Lawesson's reagent in THF.

Sources & evidence

ORD record
ord-9f724c4a195d44378d427a472acfaec1
Source dataset
uspto-grants-2010_03
Patent number
US07674801B2

Reaction notes

Loading…