Lawesson's reagent → HCID 59208479, compound

HRID 2243066Notes

Reaction equation

HRID 2243066 reaction equation
[Br:1][C:2]1[C:3]([C:14](=[S:16])[NH2:15])=[CH:4][C:5]([NH:8][C:9]([NH:11][CH2:12][CH3:13])=[O:10])=[N:6][CH:7]=1.CO[C:19]1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=S)=C[CH:24]=1>C1COCC1>[Br:1][C:2]1[C:3]([C:14](=[S:16])[NH2:15])=[CH:4][C:5]([NH:8][C:9]([NH:11][CH:12]([CH2:19][CH3:24])[CH3:13])=[O:10])=[N:6][CH:7]=1

Participants

4

Reactant 2

HCID 87949Lawesson's reagentHCID 59208439AZD7118 Bromo Thioamide

Product 1

HCID 59208479HCID 59208479, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The title compound was synthesized by a method analogous to the synthesis of Intermediate 42 starting with Intermediate 50 and Lawessons reagent in THF. MS (ESP): 332 (M+1) for C11H15BrN4OS

Sources & evidence

ORD record
ord-e871339403004a4e86694f29992d9943
Source dataset
uspto-grants-2010_03
Patent number
US07674801B2

Reaction notes

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