Maleic Acid → HCID 178465560, compound

HRID 2243079Notes

Reaction equation

HRID 2243079 reaction equation
[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]\[C:4]([OH:6])=[O:5].[C:9]1([C:15]2[S:16][C:17]3[CH:23]=[C:22]([NH:24][C:25](=[NH:27])[CH3:26])[CH:21]=[CH:20][C:18]=3[N:19]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>CC(C)=O>[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]\[C:4]([OH:6])=[O:5].[C:9]1([C:15]2[S:16][C:17]3[CH:23]=[C:22]([NH:24][C:25](=[NH:27])[CH3:26])[CH:21]=[CH:20][C:18]=3[N:19]=2)[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1

Participants

4

Reactant 2

HCID 444266Maleic AcidHCID 178465559HCID 178465559, compound

Product 1

HCID 178465560HCID 178465560, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

A 1M solution of maleic acid in acetone (10 ml) is added dropwise to N-(2-phenylbenzothiazol-6-yl)acetamidine (1 g, 0.00374 mol) (Example 1), in acetone (30 ml). The product is precipitated and filtered off. Yield: 1.09 g (77%); Elem. anal. C15H13N3S.C4H4O4; theory C, 59.51; H, 4.47; N, 10.96. found C, 59.30; H, 4.36; N, 10.62. IR (KBr): 3060, 1700, 1480, 1360 cm−1.

Workup

  1. customThe product is precipitated
  2. filtrationfiltered off

Sources & evidence

ORD record
ord-16884cf5eb024d7eb7308593a19761f2
Source dataset
uspto-grants-2010_03
Patent number
US07674809B2

Reaction notes

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