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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 224321Generated: October 29, 2026

(4-Fluoro-3-phenoxyphenyl)methanol → Valine, N-[4-(trifluoromethyl)phenyl]-

https://huagongshe.com/reaction/224321

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Fluoro-3-phenoxyphenyl)methanolHCID 12874224—
Reactant3-(4-Trifluoromethylphenyl)-4-isopropyloxazolidine-2,5-dioneHCID 20482786—
ProductValine, N-[4-(trifluoromethyl)phenyl]-HCID 13388454—

Reaction Steps

In the same way, 3-(4-trifluoromethylphenyl)-4-isopropyloxazolidine-2, 5-dione is reacted with 4-fluoro-3-phenoxybenzyl alcohol to give the 4-fluoro-3-phenoxybenzyl ester of N-(4-trifluoromethylphenyl) valine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04231953
Source datasetuspto-grants-1980_11
ORD IDord-33d7ea2fee0e40289ae3020a5048ae6f
Source noteuspto-grants-1980_11