Hydrazine hydrate (1:1) → [(3-Methyl-4-nitrophenyl)methyl]hydrazine

HRID 2243269Notes

Reaction equation

HRID 2243269 reaction equation
O.[NH2:2][NH2:3].[CH3:4][C:5]1[CH:6]=[C:7]([CH:10]=[CH:11][C:12]=1[N+:13]([O-:15])=[O:14])[CH2:8]Cl>C(O)C>[CH3:4][C:5]1[CH:6]=[C:7]([CH:10]=[CH:11][C:12]=1[N+:13]([O-:15])=[O:14])[CH2:8][NH:2][NH2:3]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 87687Alpha-chloro-3-methyl-4-nitrotoluene

Product 1

HCID 20367228[(3-Methyl-4-nitrophenyl)methyl]hydrazineYield 96.6%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

To an ethanol solution (60 ml) of hydrazine monohydrate (5.00 g), an ethanol solution (20 ml) of 3-methyl-4-nitrobenzyl chloride (3.71 g) was added dropwise while refluxing it, and the mixture was continuously refluxed for 6 hours. After finishing the reaction, the solvent was distilled off and (3-methyl-4-nitrobenzyl)-hydrazine (3.50 g) was obtained.

Workup

  1. temperaturewhile refluxing it
  2. temperaturethe mixture was continuously refluxed for 6 hours
  3. customthe reaction
  4. distillationthe solvent was distilled off

Sources & evidence

ORD record
ord-62f1e9f7af914e6d8e790c237abb3dfa
Source dataset
uspto-grants-2010_03
Patent number
US07674807B2

Reaction notes

Loading…