反应详情

3,4-Dimethoxyphenylacetic acid (6.47 g, 0.033 mole) was dissolved in 50 ml of dry benzene and refluxed for 2 hr. with excess thionyl chloride (25 ml). The solvent and SOCl2 were removed on a rotary evaporator. Two additional quantities of dry benzene were added to the residue, followed by rotary evaporation which yielded 3,4-dimethoxyphenylacetyl chloride.

1. temperaturerefluxed for 2 hr
2. customThe solvent and SOCl2 were removed on a rotary evaporator
3. additionTwo additional quantities of dry benzene were added to the residue
4. customfollowed by rotary evaporation which