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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 224334Generated: October 30, 2026

Potassium Bicarbonate → Acetamide, 2-(3,4-dimethoxyphenyl)-N-(2-(5-methoxyindan-6-yl)ethyl)-

https://huagongshe.com/reaction/224334

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium BicarbonateHCID 516893—
Reactant(3,4-Dimethoxyphenyl)acetyl chlorideHCID 3604458—
ReactantHCID 12426123HCID 12426123—
ProductAcetamide, 2-(3,4-dimethoxyphenyl)-N-(2-(5-methoxyindan-6-yl)ethyl)-HCID 3051194—

Reaction Steps

5-Aminoethyl-6-methoxyindan and 3,4-dimethoxyphenylacetyl chloride were reacted following the procedure of Example 1, except that potassium bicarbonate was used in place of triethylamine, to produce the desired product. After recrystallization from ethanol it melted at 115° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04232014
Source datasetuspto-grants-1980_11
ORD IDord-cc218c9b27d043f488071459b576483d
Source noteuspto-grants-1980_11