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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2243445Generated: November 1, 2026

1-Tert-butyl 4-chloromethyl piperidine-1,4-dicarboxylate → 4-Piperidinecarboxylic acid

https://huagongshe.com/reaction/2243445

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Tert-butyl 4-chloromethyl piperidine-1,4-dicarboxylateHCID 10107566—
ReactantHCID 16122817HCID 16122817—
Product4-Piperidinecarboxylic acidHCID 3773—

Reaction Steps

Prepared from 3-chloro-4-(2-cyclopentyl-acetylamino)-N-thiazol-2-yl-benzamide and piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-chloromethyl ester followed by deprotection.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07674912B2
Source datasetuspto-grants-2010_03
ORD IDord-f31094c4d411494a8d7c5aa52e5fa3cd
Source noteuspto-grants-2010_03