Water → HCID 11619096, compound

HRID 2243487Notes

Reaction equation

HRID 2243487 reaction equation
C[O:2][C:3]([C:5]1[S:26][C:8]2[C:9]3[CH:10]=[CH:11][C:12]([C:16](=[O:25])[NH:17][CH2:18][C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=4)=[CH:13][C:14]=3[S:15][C:7]=2[C:6]=1[O:27][CH2:28][C:29]([O:31]CC)=[O:30])=[O:4].O>C1COCC1>[CH2:18]([NH:17][C:16]([C:12]1[CH:11]=[CH:10][C:9]2[C:8]3[S:26][C:5]([C:3]([OH:4])=[O:2])=[C:6]([O:27][CH2:28][C:29]([OH:31])=[O:30])[C:7]=3[S:15][C:14]=2[CH:13]=1)=[O:25])[C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1

Participants

4

Reactant 2

HCID 962WaterHCID 68543909HCID 68543909, compound

Product 1

HCID 11619096HCID 11619096, compoundYield 63%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following General Procedure A, 6-benzylcarbamoyl-1-ethoxycarbonylmethoxy-3,8-dithia-cyclopenta[a]indene-2-carboxylic acid methyl ester (9 mg, 0.02 mmol) was stirred in THF (1 ml) and water (1 ml) for 17 hr. Work-up yielded 5 mg (63%) of title compounds as a light yellow solid.

Sources & evidence

ORD record
ord-85433b59c8324f98921ffa241df9c8ad
Source dataset
uspto-grants-2010_03
Patent number
US07674822B2

Reaction notes

Loading…