Lithium Hydroxide → HCID 11718381, compound

Participants

Reaction Steps

To a solution of 6-cyclohexylamino-1-ethoxycarbonylmethoxy-3,8-dithia-cyclopenta[a]indene-2-carboxylic acid methyl ester (23 mg, 0.05 mmol) in THF/H20 was added 2.OM aq. LiOH solution (0.125 mL, 0.25 mmol) at room temperature. After stirring at this tempterature overnight, the reaction mixture was concentrated, and acidified with 10% HCl. The product was collected by filtration and washed with water as a white solid (13.2 mg, 63%).

Provenance & Evidence