Allyl bromide → HCID 67041439, compound

HRID 2243774Notes

Reaction equation

HRID 2243774 reaction equation
[CH3:1][N:2]1[C:7]([CH3:8])=[CH:6][C:5]([CH3:9])=[N:4][C:3]1=[O:10].[CH2:11]([Br:14])[CH:12]=[CH2:13]>C(#N)C>[Br-:14].[CH2:11]([NH+:4]1[C:5]([CH3:9])=[CH:6][CH:7]([CH3:8])[N:2]([CH3:1])[C:3]1=[O:10])[CH:12]=[CH2:13]

Participants

4

Reactant 2

HCID 7841Allyl bromideHCID 853977HCID 853977, compound

Product 1

HCID 67041439HCID 67041439, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A mixture of 8.0 g (0.058 mol) of 1,4,6-trimethylpyrimidin-2(1H)-one and 14.0 g (0.116 mol) of allyl bromide were heated together under reflux in acetonitrile for 16 hours under an inert gas atmosphere. After cooling, a violet solid precipitated out, which was filtered off with suction. The product was purified by recrystallization from chloroform/diethyl ether.

Workup

  1. temperaturewere heated together
  2. temperatureAfter cooling
  3. customa violet solid precipitated out
  4. filtrationwhich was filtered off with suction
  5. customThe product was purified by recrystallization from chloroform/diethyl ether

Sources & evidence

ORD record
ord-ef11cbd779d548d08125be7732e06cd8
Source dataset
uspto-grants-2010_03
Patent number
US07678156B2

Reaction notes

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